Understanding Molecular Mechanisms of Adaptation and Improving Health by Optimizing Exercise
|Learning How to Get Fit|
of the primary aims of our research program is to understand what types
of exercise training is are capable of improving fitness. We are
particularly interested in the intensities of recreational sport and
whole body high intensity interval training that are required
to improve aerobic capacity and exercise performance.
|Understanding Mechanisms to Optimize Exercise |
ability of exercise to improve whole body fitness has been known
for decades. However, the intensity that will elicit the
greatest increase in fitness remains unknown. We are currently
conducting a variety of studies aimed at both establishing the optimial
training intesnity, and understanding the underlying mechanisms
(both metabolic and cardiovascular) that make this intensity optimal.
|Molecular Control of Mitochondrial Biogenesis|
of our research energy is focused on understanding the molcular mechanisms
that control mitochondrial content and function in skeletal muscle and
adipose tissue. Specifically we are examining the roles that
SIRT1, PGC-1a and mTOR play in inducing mitochondrial biogenesis following a
range of pharmacological, nutritional and exercise interventions.
|Translating Basic Research from the Lab to the Community|
are also interested in sharing the knowledge we are gaining from our
primary research with both the Kingston community and the Canadian
population whenever possible. This translational work takes many
forms including media interviews and research conducted in applied
settings. For examples of this work check out the "Outside the
Lab" link at the top of the page.
School of Kinesiology and Health Studies
28 Division St.,Queen's University, Kingston, Ontario, Canada. K7L 3N6.